SPECIFICATION

Chemical Name	Tetrahydrofuran
Molecular Formula	C₄H₈O
CAS Number	25190-06-1
Appearance	Colorless Liquid, Faint Ethereal Odor
Grade Standard	Industrial Grade
Solubility	7.3 g/l

Melting Point Boiling Point Density	-108℃ 66℃ 0.889 g/cm

Purity	99.5%

etrahydrofuran (THF): Properties, Uses, Availability, and Safety

Introduction

Tetrahydrofuran (THF) is a versatile, colorless liquid widely used in modern industry. As an important solvent, THF plays a significant role in the production of plastics, pharmaceuticals, and other chemicals. This article examines the properties, applications, availability, and safe handling of Tetrahydrofuran, providing essential information for buyers and users.

Properties of Tetrahydrofuran

Chemical Formula and Structure

THF’s chemical formula is C₄H₈O. Structurally, it features a five-membered ring with four carbon atoms and one oxygen atom, resulting in its excellent solvent capabilities.

Physical Properties

Tetrahydrofuran is a clear, highly volatile liquid. It has a boiling point of about 66°C and a melting point close to -108°C. THF is completely miscible with water and most organic solvents, making it easy to use in various chemical processes.

Chemical Properties

THF is known for its strong solvency, high reactivity, and ability to dissolve both polar and nonpolar substances. It is highly flammable and can form explosive peroxides if not stored correctly.

Uses of Tetrahydrofuran

Solvent in Chemical Reactions

THF is a preferred solvent for polymerization and Grignard reactions. It helps dissolve a wide range of compounds and promotes efficient chemical transformations.

Pharmaceutical Industry

In pharmaceuticals, THF is used to synthesize active ingredients and intermediates. Its purity and reactivity make it ideal for producing high-quality medicines.

Other Industrial Applications

Besides chemicals and pharmaceuticals, THF is also used in adhesives, coatings, and as a cleaning agent. Its versatility ensures that it remains in high demand across various sectors.

Availability of Tetrahydrofuran for Sale

Suppliers in the Market

Many reputable chemical suppliers offer Tetrahydrofuran for sale, including Brand Chemical Supplies and other leading companies. Buyers should always confirm the supplier’s credentials and delivery capabilities.

Grades and Purities

THF is available in several grades, such as industrial, laboratory, and pharmaceutical. Purity levels typically range from 99% to 99.9%, depending on the intended application.

Buying Considerations

When purchasing THF, consider purity, packaging, price, and supplier reputation. Always request a certificate of analysis to ensure you receive the correct product for your needs.

Safety Considerations for Tetrahydrofuran

Health Hazards

Exposure to THF can cause irritation of the eyes, skin, and respiratory tract. Inhalation of high concentrations may lead to dizziness, headache, or even unconsciousness.

Storage and Handling

Store THF in tightly sealed containers, away from heat, sparks, and open flames. Because it can form explosive peroxides, monitor storage times and use stabilizers when necessary.

Personal Protective Equipment

Always wear gloves, safety goggles, and lab coats when handling THF. Work in a well-ventilated area or use fume hoods to minimize exposure.

 

Conclusion

Tetrahydrofuran is a vital solvent with broad industrial and pharmaceutical applications. Understanding its properties, proper uses, and safety measures is essential for effective and safe operation. When sourcing THF, prioritize reputable suppliers and always follow recommended safety guidelines to ensure a reliable and secure chemical supply.